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Deficiency of α-1-antitrypsin influences systemic iron homeostasis

There is evidence that proteases and antiproteases participate in the iron homeostasis of cells and living systems. We tested the postulate that α-1 antitrypsin (A1AT) polymorphism and the consequent deficiency of this antiprotease in humans are associated with a systemic disruption in iron homeosta...

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Detalhes bibliográficos
Main Authors: Ghio, Andrew J, Soukup, Joleen M, Richards, Judy H, Fischer, Bernard M, Voynow, Judith A, Schmechel, Donald E
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556862/
https://ncbi.nlm.nih.gov/pubmed/23378755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S37897
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