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Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury

Air pollutants cause changes in iron homeostasis through: 1) a capacity of the pollutant, or a metabolite(s), to complex/chelate iron from pivotal sites in the cell or 2) an ability of the pollutant to displace iron from pivotal sites in the cell. Through either pathway of disruption in iron homeost...

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Détails bibliographiques
Publié dans:Free Radic Biol Med
Auteurs principaux: Ghio, Andrew J., Soukup, Joleen M., Dailey, Lisa A., Madden, Michael C.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274387/
https://ncbi.nlm.nih.gov/pubmed/32092410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.02.007
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