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TISSUE SPECIFIC RESPONSES TO ABERRANT FGF SIGNALING IN COMPLEX HEAD PHENOTYPES
BACKGROUND: The role of fibroblast growth factor and receptor (FGF/FGFR) signaling in bone development is well studied, partly because mutations in FGFRs cause human diseases of achondroplasia and FGFR-related craniosynostosis syndromes including Crouzon syndrome. The FGFR2c C342Y mutation is a freq...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556393/ https://ncbi.nlm.nih.gov/pubmed/23172727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23903 |
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