Imaging of Glutamate Neurotransmitter Alterations in Alzheimer’s Disease

Glutamate (Glu) is a major excitatory neurotransmitter in brain and has been shown to decrease in the early stages of Alzheimer’s disease (AD). Using glutamate amine exchange saturation transfer (GluCEST) method, we imaged the change in [Glu] in APP-PS1 transgenic mouse model of AD at high spatial r...

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Autori principali: Haris, Mohammad, Nath, Kavindra, Cai, Kejia, Singh, Anup, Crescenzi, Rachelle, Kogan, Feliks, Verma, Gaurav, Reddy, Sanjana, Hariharan, Hari, Melhem, Elias R., Reddy, Ravinder
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556355/
https://ncbi.nlm.nih.gov/pubmed/23045158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2875
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