Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development

The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and give rise to epidermal permeability barrier (EPB). EPB defects play an important role in the pathophysiology of skin diseases such as eczema. The tr...

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Bibliographic Details
Main Authors: Wang, Zhixing, Kirkwood, Jay S., Taylor, Alan W., Stevens, Jan F., Leid, Mark, Ganguli-Indra, Gitali, Indra, Arup K.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556343/
https://ncbi.nlm.nih.gov/pubmed/23096701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.358
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