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Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development

The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and give rise to epidermal permeability barrier (EPB). EPB defects play an important role in the pathophysiology of skin diseases such as eczema. The tr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Zhixing, Kirkwood, Jay S., Taylor, Alan W., Stevens, Jan F., Leid, Mark, Ganguli-Indra, Gitali, Indra, Arup K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556343/
https://ncbi.nlm.nih.gov/pubmed/23096701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.358
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