A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31

The cytoplasmic Elmo1:Dock180 complex acts as a guanine nucleotide exchange factor (GEF) for the small GTPase Rac and functions downstream of the phagocytic receptor BAI1 during apoptotic cell clearance, and in the entry of Salmonella and Shigella into cells [1–7]. We discovered an unexpected bindin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mauldin, Joshua P., Lu, Mingjian, Das, Soumita, Park, Daeho, Ernst, Peter B., Ravichandran, Kodi S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556191/
https://ncbi.nlm.nih.gov/pubmed/23273896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.11.049
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