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The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell cycle arrest after DNA damage
The RNA helicase p68 (DDX5) is an established co-activator of the p53 tumour suppressor that itself plays a pivotal role in orchestrating the cellular response to DNA damage. Although several factors influence the biological outcome of p53 activation, the mechanisms governing the choice between cell...
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Asıl Yazarlar: | , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2012
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3556166/ https://ncbi.nlm.nih.gov/pubmed/22986526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.426 |
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