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A new strategy based on pharmacophore-based virtual screening in adenosine deaminase inhibitors detection and in-vitro study

BACKGROUND AND THE PURPOSE OF THE STUDY: Adenosine deaminase (ADA) inhibition not only may be applied for the treatment of ischemic injury, hypertension, lymphomas and leukaemia, but also they have been considered as anti- inflammatory drugs. On the other hand according to literatures, ADA inhibitor...

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Detalhes bibliográficos
Main Authors: Bazl, Roya, Ganjali, Mohammad Reza, Saboury, Ali-akbar, Foroumadi, Alireza, Nourozi, Parviz, Amanlou, Massoud
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556010/
https://ncbi.nlm.nih.gov/pubmed/23351306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-20-64
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