Three-component synthesis of pyrano[2,3-d]-pyrimidine dione derivatives facilitated by sulfonic acid nanoporous silica (SBA-Pr-SO(3)H) and their docking and urease inhibitory activity

BACKGROUND: A straightforward and efficient method for the synthesis of pyrano[2,3-d]pyrimidine diones derivatives from the reaction of barbituric acid, malononitrile and various aromatic aldehydes using SBA-Pr-SO(3)H as a nanocatalyst is reported. RESULTS: Reactions proceed with high efficiency und...

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Detalhes bibliográficos
Main Authors: Ziarani, Ghodsi Mohammadi, Faramarzi, Sakineh, Asadi, Shima, Badiei, Alireza, Bazl, Roya, Amanlou, Massoud
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584946/
https://ncbi.nlm.nih.gov/pubmed/23351402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-21-3
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