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Bone marrow-induced Mef2c deficiency delays B-cell development and alters the expression of key B-cell regulatory proteins
The Mef2 family transcriptional regulator Mef2c (myocyte enhancer factor 2c) is highly expressed in maturing bone marrow and peripheral mature B-cells. To evaluate the role of this transcription factor in B-cell development, we generated a B-cell-specific conditional deletion of Mef2c using the Mb-1...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555695/ https://ncbi.nlm.nih.gov/pubmed/23087187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxs088 |
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