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The in vitro derivation of phenotypically mature and diverse B cells from immature spleen and bone marrow precursors

The capacity of immature B cells of the spleen and bone marrow to differentiate in vitro into cells representing mature end stage cells was investigated using BAFF and Notch pathway activators. Immature splenic and bone marrow B cells were found, in the presence of both of these activators, to matur...

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Detalhes bibliográficos
Main Authors: Roundy, Kirstin M., Jacobson, Amanda C., Weis, Janis J., Weis, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040573/
https://ncbi.nlm.nih.gov/pubmed/20077404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939661
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