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The in vitro derivation of phenotypically mature and diverse B cells from immature spleen and bone marrow precursors

The capacity of immature B cells of the spleen and bone marrow to differentiate in vitro into cells representing mature end stage cells was investigated using BAFF and Notch pathway activators. Immature splenic and bone marrow B cells were found, in the presence of both of these activators, to matur...

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Bibliografiske detaljer
Main Authors: Roundy, Kirstin M., Jacobson, Amanda C., Weis, Janis J., Weis, John H.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040573/
https://ncbi.nlm.nih.gov/pubmed/20077404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939661
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