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Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model
BACKGROUND: Defects in keratinocyte differentiation and skin barrier are important features of inflammatory skin diseases like atopic dermatitis. Mast cells and their main mediator histamine are abundant in inflamed skin and thus may contribute to disease pathogenesis. METHODS: Human primary keratin...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Blackwell Publishing Ltd
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3555427/ https://ncbi.nlm.nih.gov/pubmed/23157658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.12051 |
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