Ablation of the calcium-sensing receptor in keratinocytes impairs epidermal differentiation and barrier function

The calcium-sensing receptor (CaR) plays an essential role in mediating Ca(2+)-induced keratinocyte differentiation in vitro. In this study, we generated keratinocyte-specific CaR knockout ((Epid)CaR-/-) mice to investigate the function of the CaR in epidermal development in vivo. (Epid)CaR-/- mice...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Tu, Chia-Ling, Crumrine, Debra, Man, Mao-Qiang, Chang, Wenhan, Elalieh, Hashem, You, Michael, Elias, Peter M., Bikle, Daniel D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434298/
https://ncbi.nlm.nih.gov/pubmed/22622426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.159
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi