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Role of caveolin-1 expression in the pathogenesis of pulmonary edema in ventilator-induced lung injury

Caveolin-1 is a key regulator of pulmonary endothelial barrier function. Here, we tested the hypothesis that caveolin-1 expression is required for ventilator-induced lung injury (VILI). Caveolin-1 gene-disrupted (Cav-1(-/-)) and age-, sex-, and strain-matched wild-type (WT) control mice were ventila...

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Detalhes bibliográficos
Main Authors: Maniatis, Nikolaos A., Kardara, Matina, Hecimovich, Dan, Letsiou, Eleftheria, Castellon, Maricela, Roussos, Charalambos, Shinin, Vasily, Votta-Vellis, E. Gina, Schwartz, David E., Minshall, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555415/
https://ncbi.nlm.nih.gov/pubmed/23372929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-8932.105033
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