FLT3/ITD associated with an immature immunophenotype in PML-RARα leukemia

Acute promyelocytic leukemia (APL) is characterized by the specific PML-RARα fusion gene resulting from translocation t(15;17) (q22;q12). Internal tandem duplication (ITD) of the FLT3 gene has been observed in approximately 35% of APLs, and large-scale studies have identified the presence of ITD as...

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Main Authors: Takenokuchi, Mariko, Kawano, Seiji, Nakamachi, Yuji, Sakota, Yasuyuki, Syampurnawati, Meilani, Saigo, Katsuyasu, Tatsumi, Eiji, Kumagai, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: PAGEPress Publications 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555210/
https://ncbi.nlm.nih.gov/pubmed/23355940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/hr.2012.e22
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