A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms

Aim: The glutathione-dependent AdhC-EstD formaldehyde detoxification system is found in eukaryotes and prokaryotes. It is established that it confers protection against formaldehyde that is produced from environmental sources or methanol metabolism. Thus, its presence in the human host-adapted bacte...

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Autori principali: Chen, Nathan H., Couñago, Rafael M., Djoko, Karrera Y., Jennings, Michael P., Apicella, Michael A., Kobe, Bostjan, McEwan, Alastair G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2013
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555115/
https://ncbi.nlm.nih.gov/pubmed/22937752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4749
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