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Serine Arginine Splicing Factor 3 Is Involved in Enhanced Splicing of Glucose-6-phosphate Dehydrogenase RNA in Response to Nutrients and Hormones in Liver

Expression of G6PD is controlled by changes in the degree of splicing of the G6PD mRNA in response to nutrients in the diet. This regulation involves an exonic splicing enhancer (ESE) in exon 12 of the mRNA. Using the G6PD model, we demonstrate that nutrients and hormones control the activity of ser...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Walsh, Callee M., Suchanek, Amanda L., Cyphert, Travis J., Kohan, Alison B., Szeszel-Fedorowicz, Wioletta, Salati, Lisa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554946/
https://ncbi.nlm.nih.gov/pubmed/23233666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.410803
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