Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity

Nuclear speckles are subnuclear storage sites containing pre-mRNA splicing machinery. Proteins assembled in nuclear speckles are known to modulate transcription and pre-mRNA processing. We have previously identified nuclear speckle-related protein 70 (NSrp70) as a novel serine/arginine (SR)-related...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kim, Chang-Hyun, Kim, Young-Dae, Choi, Eun-Kyung, Kim, Hye-Ran, Na, Bo-Ra, Im, Sin-Hyeog, Jun, Chang-Duk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813587/
https://ncbi.nlm.nih.gov/pubmed/26797131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.689414
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