The V499G/Y501H Mutation Impairs Fast Motor Kinetics of Prestin and Has Significance for Defining Functional Independence of Individual Prestin Subunits

Outer hair cells (OHCs) are a mammalian innovation for mechanically amplifying sound energy to overcome the viscous damping of the cochlear partition. Although the voltage-dependent OHC membrane motor, prestin, has been demonstrated to be essential for mammalian cochlear amplification, the molecular...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Homma, Kazuaki, Duan, Chongwen, Zheng, Jing, Cheatham, Mary Ann, Dallos, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554914/
https://ncbi.nlm.nih.gov/pubmed/23212912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.411579
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi