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Influence of intragenic CCL3 haplotypes and CCL3L copy number in HIV-1 infection in a sub-Saharan African population

Two CCL3 haplotypes (HapA1 and Hap-A3) and two polymorphic positions shared by the haplotypes (Hap-2SNP) were investigated together with CCL3L copy number (CN), for their role in HIV-1 disease. Hap-A1 was associated with protection from in utero HIV-1 infection: exposed-uninfected infants had higher...

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Detalhes bibliográficos
Main Authors: Paximadis, Maria, Schramm, Diana B, Gray, Glenda E., Sherman, Gayle, Coovadia, Ashraf, Kuhn, Louise, Tiemessen, Caroline T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554858/
https://ncbi.nlm.nih.gov/pubmed/23151487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2012.51
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