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Stability of Zinc Finger Nuclease Protein Is Enhanced by the Proteasome Inhibitor MG132

BACKGROUND: Zinc finger nucleases (ZFNs) are powerful tools for gene therapy and genetic engineering. The characterization of ZFN protein stability and the development of simple methods to improve ZFN function would facilitate the application of this promising technology. However, the factors that a...

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Detalhes bibliográficos
Main Authors: Ramakrishna, Suresh, Kim, Young-Hoon, Kim, Hyongbum
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554775/
https://ncbi.nlm.nih.gov/pubmed/23365657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054282
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