Transgenic Overexpression of 14-3-3 Zeta Protects Hippocampus against Endoplasmic Reticulum Stress and Status Epilepticus In Vivo

14-3-3 proteins are ubiquitous molecular chaperones that are abundantly expressed in the brain where they regulate cell functions including metabolism, the cell cycle and apoptosis. Brain levels of several 14-3-3 isoforms are altered in diseases of the nervous system, including epilepsy. The 14-3-3...

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Autors principals: Brennan, Gary P., Jimenez-Mateos, Eva M., McKiernan, Ross C., Engel, Tobias, Tzivion, Guri, Henshall, David C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554740/
https://ncbi.nlm.nih.gov/pubmed/23359526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054491
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