Fine Tuning Inflammation at the Front Door: Macrophage Complement Receptor 3-mediates Phagocytosis and Immune Suppression for Francisella tularensis

Complement receptor 3 (CR3, CD11b/CD18) is a major macrophage phagocytic receptor. The biochemical pathways through which CR3 regulates immunologic responses have not been fully characterized. Francisella tularensis is a remarkably infectious, facultative intracellular pathogen of macrophages that c...

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Bibliografiske detaljer
Main Authors: Dai, Shipan, Rajaram, Murugesan V. S., Curry, Heather M., Leander, Rachel, Schlesinger, Larry S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554622/
https://ncbi.nlm.nih.gov/pubmed/23359218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003114
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