Evasion of Complement-Mediated Lysis and Complement C3 Deposition Are Regulated by Francisella tularensis Lipopolysaccharide O Antigen

The bacterium Francisella tularensis (Ft) is a potential weapon of bioterrorism when aerosolized. Macrophage infection is necessary for disease progression and efficient phagocytosis by human macrophages requires serum opsonization by complement. Microbial complement activation leads to surface depo...

Full description

Saved in:
Bibliographic Details
Main Authors: Clay, Corey D., Soni, Shilpa, Gunn, John S., Schlesinger, Larry S.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782685/
https://ncbi.nlm.nih.gov/pubmed/18832715
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items