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c-Jun NH(2)-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy

Embryos exposed to high glucose exhibit aberrant maturational and cytoarchitectural cellular changes, implicating cellular organelle stress in diabetic embryopathy. c-Jun-N-terminal kinase 1/2 (JNK1/2) activation is a causal event in maternal diabetes–induced neural tube defects (NTD). However, the...

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Hlavní autoři: Li, Xuezheng, Xu, Cheng, Yang, Peixin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554374/
https://ncbi.nlm.nih.gov/pubmed/22961085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0026
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