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β-Cell Failure in Type 2 Diabetes: A Case of Asking Too Much of Too Few?
The islet in type 2 diabetes (T2DM) is characterized by a deficit in β-cells, increased β-cell apoptosis, and extracellular amyloid deposits derived from islet amyloid polypeptide (IAPP). In the absence of longitudinal studies, it is unknown if the low β-cell mass in T2DM precedes diabetes onset (is...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Diabetes Association
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554362/ https://ncbi.nlm.nih.gov/pubmed/23349537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1326 |
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