Targeted Disruption of Inducible Nitric Oxide Synthase Protects Against Aging, S-Nitrosation, and Insulin Resistance in Muscle of Male Mice

Accumulating evidence has demonstrated that S-nitrosation of proteins plays a critical role in several human diseases. Here, we explored the role of inducible nitric oxide synthase (iNOS) in the S-nitrosation of proteins involved in the early steps of the insulin-signaling pathway and insulin resist...

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Autors principals: Ropelle, Eduardo R., Pauli, José R., Cintra, Dennys E., da Silva, Adelino S., De Souza, Cláudio T., Guadagnini, Dioze, Carvalho, Bruno M., Caricilli, Andrea M., Katashima, Carlos K., Carvalho-Filho, Marco A., Hirabara, Sandro, Curi, Rui, Velloso, Lício A., Saad, Mario J.A., Carvalheira, José B.C.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554348/
https://ncbi.nlm.nih.gov/pubmed/22991447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0339
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