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Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats

Early evidence demonstrates that exogenous nitric oxide (NO) and the NO produced by inducible nitric oxide synthase (iNOS) can induce insulin resistance. Here, we investigated whether this insulin resistance, mediated by S-nitrosation of proteins involved in early steps of the insulin signal transdu...

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Dettagli Bibliografici
Autori principali: Pauli, José R, Ropelle, Eduardo R, Cintra, Dennys E, Carvalho-Filho, Marco A, Moraes, Juliana C, De Souza, Cláudio T, Velloso, Lício A, Carvalheira, José B C, Saad, Mario J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375587/
https://ncbi.nlm.nih.gov/pubmed/17974582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.142414
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