Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4α pathway in insulin resistant mice

Protein hepatocyte nuclear factor 4α (HNF-4α) is atypically activated in the liver of diabetic rodents and contributes to hepatic glucose production. HNF-4α and Foxo1 can physically interact with each other and represent an important signal transduction pathway that regulates the synthesis of glucos...

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Detalhes bibliográficos
Main Authors: De Souza, Cláudio T, Frederico, Marisa J S, da Luz, Gabrielle, Cintra, Dennys E, Ropelle, Eduardo R, Pauli, José R, Velloso, Lício A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911223/
https://ncbi.nlm.nih.gov/pubmed/20421289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.183996
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