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A role for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes
Caspase 8 plays a dual role in the survival of T lymphocytes. Although active caspase 8 mediates apoptosis upon death receptor signaling, the loss of caspase 8 activity leads to receptor-interacting protein (RIP)-1/RIP-3-dependent necrotic cell death (necroptosis) upon TCR activation. The anti-apopt...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554340/ https://ncbi.nlm.nih.gov/pubmed/23175183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.148 |
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