Non-cell autonomous control of apoptosis by ligand-independent Hedgehog signaling in Drosophila

Hedgehog (Hh) signaling is important for development and homeostasis in vertebrates and invertebrates. Ligand-independent, deregulated Hh signaling caused by loss of negative regulators such as Patched causes excessive cell proliferation, leading to overgrowth in Drosophila and tumors in humans, inc...

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Autori principali: Christiansen, A E, Ding, T, Fan, Y, Graves, H K, Herz, H-M, Lindblad, J L, Bergmann, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554335/
https://ncbi.nlm.nih.gov/pubmed/23018595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.126
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