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Non-cell autonomous control of apoptosis by ligand-independent Hedgehog signaling in Drosophila

Hedgehog (Hh) signaling is important for development and homeostasis in vertebrates and invertebrates. Ligand-independent, deregulated Hh signaling caused by loss of negative regulators such as Patched causes excessive cell proliferation, leading to overgrowth in Drosophila and tumors in humans, inc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Christiansen, A E, Ding, T, Fan, Y, Graves, H K, Herz, H-M, Lindblad, J L, Bergmann, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554335/
https://ncbi.nlm.nih.gov/pubmed/23018595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.126
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