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Non-cell autonomous control of apoptosis by ligand-independent Hedgehog signaling in Drosophila
Hedgehog (Hh) signaling is important for development and homeostasis in vertebrates and invertebrates. Ligand-independent, deregulated Hh signaling caused by loss of negative regulators such as Patched causes excessive cell proliferation, leading to overgrowth in Drosophila and tumors in humans, inc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554335/ https://ncbi.nlm.nih.gov/pubmed/23018595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.126 |
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