Comparative Pharmacokinetics and Insulin Action for Three Rapid-Acting Insulin Analogs Injected Subcutaneously With and Without Hyaluronidase

OBJECTIVE: To compare the pharmacokinetics and glucodynamics of three rapid-acting insulin analogs (aspart, glulisine, and lispro) injected subcutaneously with or without recombinant human hyaluronidase (rHuPH20). RESEARCH DESIGN AND METHODS: This double-blind six-way crossover euglycemic glucose cl...

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Bibliographic Details
Main Authors: Morrow, Linda, Muchmore, Douglas B., Hompesch, Marcus, Ludington, Elizabeth A., Vaughn, Daniel E.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554283/
https://ncbi.nlm.nih.gov/pubmed/23043164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-0808
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