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Accelerated Insulin Pharmacokinetics and Improved Postprandial Glycemic Control in Patients With Type 1 Diabetes After Coadministration of Prandial Insulins With Hyaluronidase

OBJECTIVE: To compare the pharmacokinetics, pharmacodynamics, and safety of insulin lispro or regular human insulin (RHI) with or without recombinant human hyaluronidase (rHuPH20) administered before a standardized meal. RESEARCH DESIGN AND METHODS: In this four-way, crossover study, 22 patients wit...

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Autori principali: Hompesch, Marcus, Muchmore, Douglas B., Morrow, Linda, Vaughn, Daniel E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041204/
https://ncbi.nlm.nih.gov/pubmed/21273493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc10-1892
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