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Altered Binding Site Selection of p53 Transcription Cassettes by Hepatitis B Virus X Protein

The key cellular regulator p53 is a common target of viral oncoproteins. However, the mechanism by which p53 transcription regulation is modulated by hepatitis B virus X protein (HBx), a transcription cofactor implicated in hepatitis B virus-associated hepatocellular carcinoma (HCC), is poorly under...

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Autors principals: Chan, Cheryl, Wang, Yu, Chow, Pierce K. H., Chung, Alexander Y. F., Ooi, London L. P. J., Lee, Caroline G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554210/
https://ncbi.nlm.nih.gov/pubmed/23149944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01189-12
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