The Human Cytomegalovirus UL51 Protein Is Essential for Viral Genome Cleavage-Packaging and Interacts with the Terminase Subunits pUL56 and pUL89

Cleavage of human cytomegalovirus (HCMV) genomes as well as their packaging into capsids is an enzymatic process mediated by viral proteins and therefore a promising target for antiviral therapy. The HCMV proteins pUL56 and pUL89 form the terminase and play a central role in cleavage-packaging, but...

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Bibliographische Detailangaben
Hauptverfasser: Borst, Eva Maria, Kleine-Albers, Jennifer, Gabaev, Ildar, Babić, Marina, Wagner, Karen, Binz, Anne, Degenhardt, Inga, Kalesse, Markus, Jonjić, Stipan, Bauerfeind, Rudolf, Messerle, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554196/
https://ncbi.nlm.nih.gov/pubmed/23175377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01955-12
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