The Human Cytomegalovirus UL51 Protein Is Essential for Viral Genome Cleavage-Packaging and Interacts with the Terminase Subunits pUL56 and pUL89

Cleavage of human cytomegalovirus (HCMV) genomes as well as their packaging into capsids is an enzymatic process mediated by viral proteins and therefore a promising target for antiviral therapy. The HCMV proteins pUL56 and pUL89 form the terminase and play a central role in cleavage-packaging, but...

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Hlavní autoři: Borst, Eva Maria, Kleine-Albers, Jennifer, Gabaev, Ildar, Babić, Marina, Wagner, Karen, Binz, Anne, Degenhardt, Inga, Kalesse, Markus, Jonjić, Stipan, Bauerfeind, Rudolf, Messerle, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554196/
https://ncbi.nlm.nih.gov/pubmed/23175377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01955-12
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