Significant Reductions in Gag-Protease-Mediated HIV-1 Replication Capacity during the Course of the Epidemic in Japan

Human immunodeficiency virus type 1 (HIV-1) evolves rapidly in response to host immune selection pressures. As a result, the functional properties of HIV-1 isolates from earlier in the epidemic may differ from those of isolates from later stages. However, few studies have investigated alterations in...

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Autori principali: Nomura, Shigeru, Hosoya, Noriaki, Brumme, Zabrina L., Brockman, Mark A., Kikuchi, Tadashi, Koga, Michiko, Nakamura, Hitomi, Koibuchi, Tomohiko, Fujii, Takeshi, Carlson, Jonathan M., Heckerman, David, Kawana-Tachikawa, Ai, Iwamoto, Aikichi, Miura, Toshiyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554148/
https://ncbi.nlm.nih.gov/pubmed/23152532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02122-12
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