Requirement of the N-Terminal Activation Domain of Herpes Simplex Virus ICP4 for Viral Gene Expression

ICP4 is the major activator of herpes simplex virus (HSV) transcription. Previous studies have defined several regions of ICP4 that are important for viral gene expression, including a DNA binding domain and transactivation domains that are contained in the C-terminal and N-terminal 520 and 274 amin...

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Bibliographic Details
Main Authors: Wagner, Lauren M., Bayer, Avraham, DeLuca, Neal A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554072/
https://ncbi.nlm.nih.gov/pubmed/23135715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02844-12
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