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Macropinocytosis-Like HIV-1 Internalization in Macrophages Is CCR5 Dependent and Leads to Efficient but Delayed Degradation in Endosomal Compartments

HIV-1 endocytosis by a macropinocytosis-like mechanism has been shown to lead to productive infection in macrophages. However, little is known of this pathway. In this study, we examined HIV-1 endocytosis using biochemical approaches and imaging techniques in order to better understand the mechanism...

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Detalhes bibliográficos
Main Authors: Gobeil, Lise-Andrée, Lodge, Robert, Tremblay, Michel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554056/
https://ncbi.nlm.nih.gov/pubmed/23115275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01802-12
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