Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle

Spinal muscular atrophy is a severe motor neuron disease caused by reduced levels of the ubiquitous Survival of MotoNeurons (SMN) protein. SMN is part of a complex that is essential for spliceosomal UsnRNP biogenesis. Signal recognition particle (SRP) is a ribonucleoprotein particle crucial for co-t...

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Detalhes bibliográficos
Main Authors: Piazzon, Nathalie, Schlotter, Florence, Lefebvre, Suzie, Dodré, Maxime, Méreau, Agnès, Soret, Johann, Besse, Aurore, Barkats, Martine, Bordonné, Rémy, Branlant, Christiane, Massenet, Séverine
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553995/
https://ncbi.nlm.nih.gov/pubmed/23221635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1224
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