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Study of the Rifampin Monoresistance Mechanism in Mycobacterium tuberculosis

Rifampin (RIF) susceptibility is a key factor in determining the treatment effectiveness of the standardized treatment regimens. In Mycobacterium tuberculosis, both target gene mutation and the efflux pump play major roles in the resistance to antituberculosis drugs. By eliminating RIF-resistant str...

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Autores principales: Pang, Yu, Lu, Jie, Wang, Yufeng, Song, Yuanyuan, Wang, Shengfen, Zhao, Yanlin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553728/
https://ncbi.nlm.nih.gov/pubmed/23208715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01024-12
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