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Study of the Rifampin Monoresistance Mechanism in Mycobacterium tuberculosis

Rifampin (RIF) susceptibility is a key factor in determining the treatment effectiveness of the standardized treatment regimens. In Mycobacterium tuberculosis, both target gene mutation and the efflux pump play major roles in the resistance to antituberculosis drugs. By eliminating RIF-resistant str...

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Autors principals: Pang, Yu, Lu, Jie, Wang, Yufeng, Song, Yuanyuan, Wang, Shengfen, Zhao, Yanlin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553728/
https://ncbi.nlm.nih.gov/pubmed/23208715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01024-12
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