A Time-to-Event Pharmacodynamic Model Describing Treatment Response in Patients with Pulmonary Tuberculosis Using Days to Positivity in Automated Liquid Mycobacterial Culture

Days to positivity in automated liquid mycobacterial culture have been shown to correlate with mycobacterial load and have been proposed as a useful biomarker for treatment responses in tuberculosis. However, there is currently no quantitative method or model to analyze the change in days to positiv...

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Autori principali: Chigutsa, Emmanuel, Patel, Kashyap, Denti, Paolo, Visser, Marianne, Maartens, Gary, Kirkpatrick, Carl M. J., McIlleron, Helen, Karlsson, Mats O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553722/
https://ncbi.nlm.nih.gov/pubmed/23183433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01876-12
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