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Copper-Boosting Compounds: a Novel Concept for Antimycobacterial Drug Discovery
We and others recently identified copper resistance as important for virulence of Mycobacterium tuberculosis. Here, we introduce a high-throughput screening assay for agents that induce a copper hypersensitivity phenotype in M. tuberculosis and demonstrate that such copper-boosting compounds are eff...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3553712/ https://ncbi.nlm.nih.gov/pubmed/23254420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01781-12 |
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