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In Vitro Activity of Calcineurin and Heat Shock Protein 90 Inhibitors against Aspergillus fumigatus Azole- and Echinocandin-Resistant Strains

Due to the limited number of antifungals and the emergence of resistance, new therapies against invasive aspergillosis are needed. We show that calcineurin inhibitors are active in vitro against both azole- and echinocandin-resistant Aspergillus fumigatus strains. The heat shock protein 90 (Hsp90) i...

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Autori principali: Lamoth, Frédéric, Juvvadi, Praveen R., Gehrke, Christopher, Steinbach, William J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553695/
https://ncbi.nlm.nih.gov/pubmed/23165466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01857-12
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