Chemobiosynthesis of New Antimalarial Macrolides

We have synthesized new derivatives of the macrolide antibiotics erythromycin and azithromycin. Novel deoxysugar moieties were attached to these standard antibiotics by biotransformation using a heterologous host. The resulting compounds were tested against several standard laboratory and clinically...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goodman, Christopher D., Useglio, Mariana, Peirú, Salvador, Labadie, Guillermo R., McFadden, Geoffrey I., Rodríguez, Eduardo, Gramajo, Hugo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2013
Gaiak:
Chemistry; Biosynthesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553691/
https://ncbi.nlm.nih.gov/pubmed/23208707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01825-12
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