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Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts

Fibroblasts perform critical functions during the normal host response to tissue injury, but the inappropriate accumulation and persistent activation of these cells results in the development of tissue fibrosis. The mechanisms accounting for the aberrant accumulation of fibroblasts during fibrotic r...

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Bibliographic Details
Main Authors: Sisson, Thomas H., Maher, Toby M., Ajayi, Iyabode O., King, Jessie E., Higgins, Peter D. R., Booth, Adam J., Sagana, Rommel L., Huang, Steven K., White, Eric S., Moore, Bethany B., Horowitz, Jeffrey C.
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553664/
https://ncbi.nlm.nih.gov/pubmed/23355956
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