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Targeting the androgen receptor in the management of castration-resistant prostate cancer: rationale, progress, and future directions

Since the year 2000, tremendous progress has been made in the understanding of castration-resistant prostate cancer (crpc), a disease state now recognized to retain androgen receptor (ar)—dependency in most cases. That understanding led to the rational design of novel therapeutic agents targeting ho...

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Main Authors: Leibowitz–Amit, R., Joshua, A.M.
Format: Artigo
Jezik:Inglês
Izdano: Multimed Inc. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553559/
https://ncbi.nlm.nih.gov/pubmed/23355790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3747/co.19.1281
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